In a recent case discipline , doctors depict the unfortunate tale of a human being who evolve an allergy - like reaction to his own orgasm . The flakey and rare affliction left him unable to go after intimate and romantic relationships . But thankfully , the Dr. managed to handle his problem using a uncomplicated over - the - rejoinder antihistamine .
The condition is known as postorgasmic sickness syndrome , or POIS . sufferer ( almost always valet ) experience symptom standardized to hay fever or a influenza trace ejaculation , such as tiredness , itchy eyes , stuffy or fluid nozzle , and even memory trouble . These symptom come along after every or almost every coming , usually within seconds but sometimes up to minute later , and they can last anywhere from two to seven days .
There are many different illnesses that can affect a person ’s intimate function , but poi is specially rare . The National Institutes of Healthestimatesthat few than 1,000 people in the U.S. presently have it . And according to the authors of this up-to-the-minute case study , set to bepublishedin the November issue of Urology Case Reports , there are fewer than 60 reported cases of POIS in the aesculapian literature .

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The report describes an otherwise healthy 27 - year - one-time military man who first began to know his symptom at the age of 18 . In addition to his flu - same sickness , he would often break out into hive along his forearms after orgasms . He had seen several aesculapian providers over the years , including an ENT man , an infectious disease specializer , and multiple allergist , but nothing they offered seemed to help oneself . By the time he go through these medico , he had long been actively desist from any kind of intimate bodily process and romantic relationships .
Because of its rarity , there ’s very little known about precisely why poi encounter . But it ’s suspect to be a case of hypersensitivity chemical reaction to something within a somebody ’s ejaculate . Most people with POIS , for instance , have tested confident on peel son of a bitch trial run using their cum as the allergen . One plausible possibility is that sperm cell cells might set off this immune response , since they contain only half of the familial fabric found in most other cells . But even sterile mortal have developed POIS , suggesting that the true culprit is ordinarily some other ingredient in semen .
In this particular case , the man recalled that his first sequence happen after he had recovered from a face of acuate epididymitis , or inflammation around a specific area of the scrotum . Epididymitis is often make by a urinary parcel infection or sexually transmitted bacterial contagion . It ’s potential , the doctors speculate , that this infection countersink off a mountain chain reaction that caused his resistant organisation to become allergic to his semen from then on .

There ’s no official handling for POIS , but the Doctor of the Church resolve to try out out an antihistamine , which can tamp down down the symptom of other types of allergic reaction . Their initial treatment did n’t seem to work , but they then switched to an over - the - counter version of fexofenadine , take day by day ( the drug has long since become generic but is sell under the democratic brand name Allegra ) . Additionally , they send word the man to gradually ramp up his absolute frequency of coming . The fexofenadine worked like a good luck charm , leading to a self - report 90 % lessening in symptoms and appropriate the man to finally resume sexual activeness .
The doctors suspect that the other antihistamine may have die to help because its peak effects only last for a few hour , while fexofenadine is both long - lasting and non - sedative . But although this drug is safe , garish , and easy to take , the physician do recommend that more research be done to confirm that it can be a reliable option for those with poi .
“ Our experience demonstrates the feasibleness of treating a complex disease with a wide-eyed medicine and hopefully will be duplicate in succeeding patients , ” they wrote .

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