Is intelligence associate to an increase likeliness of unpaid drug utilization ? It ’s an interesting hypothesis , and one that ’s been gaining momentuminrecentyears .

If a unequivocal link between noetic electrical capacity and drug use of goods and services does exist , it will belike be some sentence before anyone establish one . Having said that , this much is for certain : history has more than its fair share of experimenting experimentalists . Let ’s see 10 of history ’s most influential scientific and technological visionaries , along with their drugs of pick .

10 . Sigmund Freud — CocaineTo Freud , cocain was more than a personal lunacy ; he regard it as a authentic wonder drug , and for many days was a Brobdingnagian proponent of its use in a wide array of program . In a letter written to his fianceé , Martha , Freud wrote : “ If all goes well , I will write an essay [ on cocaine ] and I expect it will acquire its position in remedy by the side of morphine and superscript to it … I take very small Elvis of it regularly against natural depression and against indigestion and with the most brainy of success . ”

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Freud write such a review , titled “ Uber Coca ” in 1884 . Interestingly , Freud ’s paper was one of the first to propose drug substitution as a therapeutic handling for addiction . While interchange morphine with cocain is something we now bonk to be counterproductive to recovery , the construct of substitution therapy persists to this twenty-four hours . ( For a great overview of Freud ’s family relationship with cocain , crack out this post by Scicurious . )

9 . Francis Crick — LSDFrancis Crick — of the DNA - structure discoveringWatson , Crick , andFranklin — reportedly told legion friends and colleagues about his LSD experiment during the meter he spent work to limit the molecular structure that houses all life ’s selective information .

In fact , in a 2004 interview , Gerrod Harker recalls talking with Dick Kemp — a close protagonist of Crick ’s — about LSD use among Cambridge academics , and tells the Daily Mail that the University ’s researchers often used LSD in small amounts as “ a mentation tool . ” Evidently , Crick at one point say Kemp that he had actually “ perceived the two-fold - helix shape while on LSD . ” [ Image viaNYT ]

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8 . Thomas Edison — Cocaine ElixersIn 1863 , French chemist Angelo Mariani invent “ Vin Mariani , ” a Bordeaux wine treated with coca leaf , the active ingredient of which is none other than cocaine . The ethanol content in the Bordeax could extract cocain from the coca leaves in concentrations exceeding 7 atomic number 12 per fluid snow leopard of wine . Thomas Edison — the prolific American artificer and notorious insomniac ( though perhaps not surprisingly ) — was one of many people of the periodknown to regularly take in the cocaine - laced philosopher’s stone .

7 . Paul Erdös — AmphetaminesPaul Erdös — well known for his hyperactivity ; his habit of work 19 - hour days , even well into his old age ; and his tendency to show up on his confrere ’ doorsteps demanding they ” open up their minds ” to mathematical dialogue — was one of the most fertile mathematicians who ever lived , publish more equal - retrospect newspaper publisher than any other mathematician in story .

His mystery ? harmonize to him , amphetamines . include here is an excerpt froma leger publish in 1998 by Erdös ’ de facto biographer , science writer Paul Hoffman , which excuse Erdös ’ proclivity for amphetamine use :

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Like all of Erdös ’s friends , [ fellow mathematician Ronald Graham ] was concerned about his drug - taking . In 1979 , Graham wager Erdös $ 500 that he could n’t stop consider amphetamines for a month . Erdös swallow the challenge , and croak dusty turkey for thirty Day . After Graham give up — and wrote the $ 500 off as a business expense — Erdös said , “ You ’ve show me I ’m not an addict . But I did n’t get any work done . I ’d get up in the morning and gaze at a blank piece of paper . I ’d have no ideas , just like an ordinary individual . You ’ve set mathematics back a calendar month . ” He promptly summarize taking oral contraceptive pill , and mathematics was the better for it .

6 . Steve Jobs — LSDLSD was a big deal for Steve Jobs . How big ? plainly , Jobs believed that experiment with LSD in the 1960s was “ one of the two or three most important things he had done in his life . ” What ’s more , he felt that there were parts of him that the citizenry he roll in the hay and worked with could not empathize , simply because they had n’t had a go at psychedelics . This latter opinion also number through in his recently - publish life story , wherein Jobs goes so far as to associate what he interpreted as Bill Gates ’ dearth of imagination with a want of psychedelic experimentation :

“ Bill is basically unimaginative and has never make up anything , which is why I think he ’s more comfortable now in philanthropy than technology . He just shamelessly ripped off other people ’s ideas . ”

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“ He ’d be a broad guy , ” Jobs says about Gates , “ if he had dropped Elvis once or sound off to an ashram when he was unseasoned . ”

5 . Bill Gates — LSDWhich is queer , because Bill Gates totallydid experiment with LSD , though an excerpt from a 1994 consultation with Playboy reveals he was much less open about it than business :

PLAYBOY : Ever take LSD?GATES : My errant youth ended a long time ago . PLAYBOY : What does that mean?GATES : That means there were things I did under the years of 25 that I terminate up not doing subsequently . PLAYBOY : One LSD chronicle involved you stare at a table and thinking the corner was go away to plunge into your eye . GATES : [ Smiles]PLAYBOY : Ah , a glimmering of acknowledgment . GATES : That was on the other side of that boundary . The young mind can portion out with certain kind of gooping around that I do n’t cerebrate at this eld I could . I do n’t think you ’re as capable of handling deficiency of eternal sleep or whatever challenges you switch at your body as you get older . However , I never lack a day of work .

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4 . John C. Lilly — LSD , KetamineNeurocientist John C. Lilly was a pioneer in the plain of electronic brain stimulus . He was the first individual to map pain and pleasure footpath in the mental capacity ; founded an full limb of scientific discipline explore interspecies communication between humans , dolphins , and whales ; make up the world ’s first sensorial deprivation modifier ; and comport all-embracing personal experiment with mind - alter drugs like LSD and Ketalar .

It bears refer that Lilly ’s experiment with interspecies communication , personal psychedelic use , and sensorial deprivationoften overlapped .

3 . Richard Feynman — LSD , Marijuana , KetamineFeynman was always careful about drug use , for fear of what it might do to his brain — giving up intoxicant , for example , when he begin to exhibit symptoms of habituation . InSurely You ’re Joking , Mr. Feynman ! , he writes,“You see , I get such playfulness out of mentation that I do n’t need to destroy this most pleasant machine that make life such a bragging kick . It ’s the same understanding that , afterward on , I was reluctant to try experiment with LSD in spite of my oddment about hallucinations . ”

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Nevertheless , Feynman ’s curiosity get the upright of him when he became acquainted with none other than John C. Lilly and his sensory loss tanks . Feynman try out briefly with LSD , ketamine , and marijuana , which he used to bring on isolation - induced hallucination more quickly than he could when sober .

2 . Kary Mullis — LSDWho , you may be asking , is Kary Mullis ? permit ’s put it this way : If you ’ve worked in a biomedical research lab since the 1980 ’s , there is an exceedingly good chance you ’ve execute a polymerase chain response ( aka PCR , the research laboratory technique that can turn a single segment of desoxyribonucleic acid into meg of indistinguishable copy ) , or are at least familiar with it . You have Mullis to give thanks for that . While Mullis did n’t invent the PCR technique , per se , he better upon it so importantly as to revolutionize the battleground of biomedical enquiry , securing himself a Nobel Prize in chemistryin the operation .

The mystery to Mullis ’ breakthrough ? In a September , 1994 consequence of California Monthly , Mullis says that he “ took plenty of LSD ” In the 60 and 1970s , going so far as to call his “ brain - opening ” experimentation with psychedelics “ much more crucial than any courses [ he ] ever took . ” A few year later , in an consultation for BBC ’s Psychedelic Science docudrama , Mullis mused aloud : “ What if I had not taken LSD ever ; would I have still invented PCR ? ” To which he respond , “ I do n’t know . I doubt it . I earnestly doubt it . ” [ Photovia ]

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1 . Carl Sagan — MarijuanaPreeminent astrophysicist and cosmologist Carl Sagan not only smoked marijuana regularly , he was also a strong advocate for its manipulation in enhancing intellectual pursuits — though not as in public as others on this tilt . Having said that , Sagandid contribute an essay to the 1971 rule book titled Marijuana Reconsidered that spoke to the virtues of marijuana function . The art object was compose under the put on name “ Mr. X. ” The identity of its true author was only revealed after Sagan ’s death .

All images , unless otherwise indicated , via Wikimedia Commons . This io9 flashback originally seem on January 16th , 2012 .

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